GraysGrays Dermatology

Melasma, Sun Spots, and Lentigines: Telling Them Apart and Choosing a Laser

2026-08-11 · Reviewed by the medical director (review date to be posted)

The short answer

Though they may look similar, melasma, sun spots (seborrheic keratoses), lentigines, and nevus of Ota are distinct diagnoses that differ in depth and character. Identifying the lesion comes first and choosing the laser second — and above all, melasma is not a lesion to blast away but one to lighten and manage over time. That principle is the starting point of any treatment plan.

What kind of lesion is my pigment?

Sun spots and seborrheic keratoses are epidermal lesions with relatively clear borders, and they tend to respond well to spot laser treatment. Melasma has blurred borders, spreads diffusely, and reacts sensitively to irritation — so it is managed with low-energy toning alongside lifestyle care (sun exposure, hormonal factors). Deep dermal pigment such as nevus of Ota requires a long-term plan with a high-power laser.

Why can't melasma be removed aggressively?

In melasma the melanocytes are in an overactive state, so excessive thermal stimulation can worsen the pigment or trigger rebound hyperpigmentation. That is why we manage it in multiple low-energy sessions, and decide on adjunct medication such as tranexamic acid based on the diagnosis.

Which devices does Grays use for pigment?

We use PicoWay (picosecond), StarWalker MaQX, QX MAX (nanosecond), and GentleMax Pro (long-pulse), matched to lesion depth and character. The reason we keep several devices is that each lesion calls for a different wavelength and pulse.

Pigmented lesions: characteristics and approach

LesionDepthCharacteristicsApproach
Sun spots / seborrheic keratosesEpidermisClear bordersSpot removal, a few sessions
MelasmaEpidermis to dermal junctionBlurred borders, sensitive to irritationLow-energy toning + ongoing care
LentiginesEpidermisSmall, dark maculesSpot removal
Nevus of OtaDermisBluish tone, broad distributionLong-term high-power laser plan

Related treatments

This guide is general medical information and does not replace an individual diagnosis. Please seek an in-person consultation for decisions about your own care.

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